| Sat 04/08/18 | Padiham v Runcorn Town | 2-5 | | | | |
| Tue 07/08/18 | Abbey Hey v Runcorn Town | 0-2 | | | | |
| Sat 11/08/18 | Hemsworth Miners Welfare v Runcorn Town | 1-1 | | | | |
| Wed 15/08/18 | Runcorn Town v Hemsworth Miners Welfare | 1-0 | | | | |
| Sat 18/08/18 | Runcorn Town v West Didsbury & Chorlton | 5-0 | | | | |
| Mon 20/08/18 | Winsford United v Runcorn Town | 1-2 | | | | |
| Sat 25/08/18 | Penistone Church v Runcorn Town | 1-3 | |  | | |
| Mon 27/08/18 | Runcorn Town v Ashton Athletic | 1-0 |  | | | |
| Fri 31/08/18 | City of Liverpool v Runcorn Town | 4-0 | | | | |
| Sat 08/09/18 | Runcorn Town v Irlam | 2-3 | | | | |
| Wed 12/09/18 | Runcorn Town v Hanley Town | 2-0 | | | | |
| Sat 15/09/18 | Runcorn Town v 1874 Northwich | 2-1 | | | | |
| Sat 22/09/18 | Barnoldswick Town v Runcorn Town | 5-1 | | | | |
| Sat 29/09/18 | Runcorn Town v Abbey Hey | 5-1 | | | | |
| Wed 03/10/18 | Runcorn Town v Congleton Town | 3-1 | | | | |
| Sat 06/10/18 | Silsden v Runcorn Town | 0-3 | | | | |
| Tue 09/10/18 | Bootle v Runcorn Town | 4-2 | | | | |
| Sat 13/10/18 | Runcorn Town v Guisborough Town | 3-3 | | | | |
| Wed 17/10/18 | Guisborough Town v Runcorn Town | 2-4 | | | | |
| Sat 20/10/18 | Charnock Richard v Runcorn Town | 0-0 | | | | |
| Sat 27/10/18 | Runcorn Town v Burscough | 2-3 | | | | |
| Fri 02/11/18 | Vauxhall Motors v Runcorn Town | 1-3 | | | | |
| Sun 11/11/18 | Northwich Victoria v Runcorn Town | 3-1 | | | | |
| Sat 17/11/18 | Northwich Victoria v Runcorn Town | 5-1 | | | | |
| Wed 21/11/18 | Runcorn Town v Charnock Richard * | 4-0 | | | | |
| Sat 24/11/18 | Runcorn Town v Squires Gate * | 2-3 | | | | |
| Sat 01/12/18 | Newcastle Benfield v Runcorn Town | 5-4 | | | | |
| Wed 12/12/18 | Runcorn Town v Padiham | 3-2 | | | | |
| Sat 15/12/18 | Runcorn Town v Irlam | 1-1 | | | | |
| Tue 18/12/18 | Burscough v Runcorn Town | 4-0 | | | | |
| Wed 26/12/18 | Runcorn Town v Whitchurch Alport | 2-1 | | | | |
| Sat 29/12/18 | West Didsbury & Chorlton v Runcorn Town | 3-1 | | | | |
| Sat 05/01/19 | Runcorn Town v Bootle | 0-2 | | | | |
| Wed 13/02/19 | Runcorn Town v Stockport County * | 0-1 | | | | |
| Sat 16/02/19 | Hanley Town v Runcorn Town * | 3-2 | | | | |
| Sat 23/02/19 | Irlam v Runcorn Town | 0-1 | | | | |
| Sat 02/03/19 | Ashton Athletic v Runcorn Town | 3-0 | | | | |
| Sat 23/03/19 | Squires Gate v Runcorn Town * | 2-0 | | | | |
| Sat 30/03/19 | Runcorn Town v Winsford United | 3-0 | | | | |
| Sat 13/04/19 | Runcorn Town v Litherland REMYCA | 1-0 | | | | |
